|
Symbol Name ID |
Tslp
thymic stromal lymphopoietin MGI:1855696 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased B cell proliferation |
colitis |
enlarged spleen |
increased spleen weight |
abnormal T-helper 2 cell differentiation |
increased susceptibility to autoimmune hemolytic anemia |
decreased eosinophil cell number |
increased CD4-positive, alpha-beta T cell number |
decreased lymphocyte cell number |
abnormal lymphocyte physiology |
abnormal B cell activation |
abnormal immunoglobulin level |
decreased IgE level |
increased IgE level |
increased IgG1 level |
decreased IgG2a level |
increased immunoglobulin level |
abnormal T-helper 2 physiology |
decreased circulating interleukin-4 level |
increased circulating interleukin-4 level |
abnormal cytokine level |
abnormal lymph node morphology |
enlarged lymph nodes |
lymph node hyperplasia |
abnormal immune system physiology |
increased interferon-gamma secretion |
abnormal interleukin secretion |
increased interleukin-13 secretion |
increased interleukin-5 secretion |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
decreased acute inflammation |
conjunctivitis |
liver inflammation |
glomerulonephritis |
respiratory system inflammation |
lung inflammation |
dermatitis |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
| Tslptm1(KOMP)Vlcg/Tslptm1(KOMP)Vlcg | ||||||||||||||||||||||||||||||||||||||||
| Tslptm1Mak/Tslptm1Mak | * | |||||||||||||||||||||||||||||||||||||||
| Tslptm1Sfz/Tslptm1Sfz | * | |||||||||||||||||||||||||||||||||||||||
| Tg(KRT5-rtTA)1Glk/0 Tg(tetO/CMV-Tslp)#Sfz/0 |
||||||||||||||||||||||||||||||||||||||||
| Tg(KRT14-Tslp)1Pcn/0 | ||||||||||||||||||||||||||||||||||||||||
| Tg(Lck-Tslp)1Chea/0 | ||||||||||||||||||||||||||||||||||||||||
| Tslptm1.1Pcn/Tslptm1.1Pcn Tg(KRT14-cre)1Ipc/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|
|
||
Analysis Tools